INTRO TO CBD
Cannabidiol (CBD) is a compound found in the plant and flower of cannabis, a plant with so much history going back thousands of years. The therapeutic properties of CBD are being confirmed by scientists and doctors around the world. CBD a safe, non-addictive substance, is one of more than a hundred “phytocannabinoids,” that is unique to the cannabis profile.
CBD is related to another important phytocannabinoid: tetrahydrocannabinol (THC), the compound that causes the high that cannabis is famous for. These two components of cannabis have been most studied by scientists.
Both CBD and THC have significant therapeutic qualities. However unlike THC, CBD does not make a person feel “stoned” or intoxicated. That’s because CBD and THC act in different ways on different receptors in the brain and body.
CBD: The Multipurpose Molecule
Many people are seeking alternatives to pharmaceuticals with harsh side effects – medicine more in synch with natural processes. By tapping into how we function biologically on a deep level, CBD can provide relief for chronic pain, anxiety, inflammation, depression and many other conditions.
Extensive scientific research – much of it sponsored by the U.S. government – and mounting anecdotal accounts from patients and physicians highlight CBD’s potential as a treatment for a wide range of maladies, including (but not limited to):
Gut disorders (colitis, Crohn’s)
Cardiovascular dysfunction (atherosclerosis, arrhythmia)
CBD has proven neuroprotective effects and its anti-cancer properties are being investigated at several academic research centers in the United States and elsewhere. A 2010 brain cancer study by California scientists found that CBD “enhances the inhibitory effects of THC on human glioblastoma cell proliferation and survival.” This means that CBD makes THC even more potent as an anticancer substance. Also in 2010, German researchers reported that CBD stimulates neurogenesis, the growth of new brain cells, in adult mammals.
HOW DOES CBD WORK?
CBD and THC interact with our bodies in a variety of ways. One of the main ways is by mimicking and augmenting the effects of the compounds in our bodies called “endogenous cannabinoids” - so named because of their similarity to compounds found in the cannabis plant. These “endocannabinoids” are part of what scientists refer to as the “endocannabinoid system.”
The discovery of the endocannabinoid system has significantly advanced our understanding of health and disease. It has major implications for nearly every area of medical science and helps to explain how and why CBD and THC are such versatile compounds – and why cannabis is such a widely consumed plant, despite its illegal status.
The endocannabinoid system plays a crucial role in regulating a broad range of physiological processes that affect our everyday experience – our mood, our energy level, our intestinal fortitude, immune activity, blood pressure, bone density, glucose metabolism, how we experience pain, stress, hunger, and more.
What happens if the endocannabinoid system doesn’t function properly? What are the consequences of a chronically deficient or overactive endocannabinoid system?
In a word, disease.
Cutting-edge science has shown that the endocannabinoid system is dysregulated in nearly all pathological conditions. Thus, it stands to reason that “modulating endocannabinoid system activity may have therapeutic potential in almost all diseases affecting humans,” as Pal Pacher and George Kunos, scientists with the U.S. National Institutes of Health (NIH), suggested in a 2014 publication.
By modulating the endocannabinoid system and enhancing endocannabinoid tone, CBD and THC can slow – or in some cases stop disease progression.